Hello, simple question. I tried to hit it with everything I have, yet it seems invincible. I can not lower its health even a bit. Any advice?

Use a Yrden sign to stun and trap the queen. Then go behind and attack its ass. It takes more damage from behind.

What i did is cast quen , go poke her 3 times , run and wait , go to her again block and poke , also try to stay behind her and poke her arse. If everything fails drop a lot of traps and she will die , no xp from trap killing tho so you should land the final blow :)

EDIT: ninjaed D:

Indeed. That's what I did as well. Except I just went and slapped it's face cause I'm brave and risky. Also if you can trap it and have throwing knives, that would be a good time to use them.

Use Quen on yourself just to be on the safe side. The Queen is a bit painful when she bites you.

I just quit the game after trying to beat the queen for about 20 times. On the best try it was at maybe 5-10% health, but I made the second mistake then and died (first mistake was 50%+ of my health).

I set up a couple of fire traps before breaking the eggs, used a bleeding oil on my robust silver sword, and kept throwing down the trap sign (yyrd?) and doing one slow attack every time the queen got trapped and rolled away. This seemed like it'd kill the queen if I just didn't make mistakes = don't let the queen hit me more than once in a 2-3min fight.

Edit: Hmm, Quen lets me do more attacks? Trying that then.

Edit 2: Actually I thought you meant the mind control Sign. All this time I had the impression that Quen just reduced damage a bit, now I realized it actuall absorbs a decent amount. This might've have helped earlier, hah. I think mostly tried Quen in the Dragon fire thing on prologue, and decided it didn't do much. :)

Thank you all, going to try now. I really wonder why I bought the book about endregas when there is not even a hint on how to kill the queen :(

Just spam Yrden, it seems to have a chance of stunning her for several seconds and you can hit her quite a few times. When I was killing her it seemed to only stun her for ~1 second every other time she hit a Yrden trap so you need to be careful.

I used a combination of bleeding oil sword attacks + Igni + running away in panic. There's a spot in the river where she can't get through 2 pillars/ stones. A bit gamey, but a good place to recover health and save :)

Make sure that before you kill the final cocoon to run around the area to make sure there aren't any additional guards, I had that issue for one of the queens. Also like I said, Yrden seemed to only have a chance to stun her for longer, half of the time it only stunned her for 1 second, the other half it stunned her for at least 4-5.

Make sure your using your silver sword (Just FYI).

Lay some traps in the direction the queen will spawn before you destroy the last cocoon.

Kill any nearby guards or soldiers before you destroy the cocoon. They will respawn every time you reload a save!

Use Quen, but realize that it prevents vigor from regenerating.

Use bombs, and oils.

Dodge, Dodge, Dodge...

If it is still to hard, change to easy to kill her. Then after the quest or the fight change it back to the desired difficulty setting.

Walk around before you kill the last cocoon to make sure you killed everything. I once died running away from 5 Nekkers with 1% hp just to walk into a trap and die. I slapped myself in the face for that Anyway....

As a last resort turn the difficulty down. Yes the Yrden trap stuns her sometimes for 1 second, sometimes for 3-4 seconds. It depends. As soon as she is not glowing purple anymore, do a rickroll I mean roll away. I ran 50% of the time and 50% I ran. If she's chasing you do a roll in front of her to distract her (she'll miss the bite) Then you can safely set up the Yrden spell. If you want to play it safe, throw your knives at her when she's trapped. A bit costly but it works.

My strategy was: Cast quen, cast trap. Then hit the queen, roll away when she's no longer trapped. Then run around until your vigor regenerates and repeat the process. I didn't die once. Do continue, you can do it!

@ C17 you said the same thing as me but better. I envy you.

There's like a ton of traps in that area, at least one of the Queens (i've not yet found the 2nd).

I collected them all then put them down on nearly the same spot, right in her path when she appears and comes at me. Then I saved, and destroyed the last cocoon. The traps damaged her like 50% to 75% of her health (I had put down at least a dozen).

After that it was just a few Yrden and some mopping up.

Alright, now that I knew how good Quen sign is, I killed the queen without taking any health damage. Played on high difficulty this far without using Quen. Oh well, at least I practiced my combat sufficiently with all those realods in some more difficult spots.

An alternative:
Just parry and strike.
I'm playing on Hard difficulty and just killed my first queen, level 7 character (so only training skill branch skills).

I tried a bunch of stuff to little effect.
Eventually I just went up, used strong attack, waited until she blocked (usually after 3 blows, but it depends), then pressed the block/parry button in preparation for her counter attack.

Occasionally she mixes it up with poison or an off-timed attack so you have to be careful (on hard a single attack would kill me most of the time), but very doable.
Obviously use the Insectoid oil to help kill her, since that should raise the damage by, what, 20%.

One key to this particular approach is upgrading the Parry skill. it's one of the "training" set of skills. If you upgrade it to 2nd level you block "100%" of damage (listed as like 520 damage reduction or something in your character profile).
Alternatively you could just roll (and I did that a couple times), but I think parrying would be easier.

Do NOT use quen for this strategy as your vigor won't replenish and you'll have to run away. I killed the queen without any potion upgrades (aside from sword oil). [I wasn't planning to fight her, I just happened into her nest.]

I can't comment on the utility of quen as I've generally stayed away from it. Anything that reduces vigor regeneration seems like it would make for slower combat. That's a personal pref. thing though.

(BTW, I died like a dozen times before I realized I could just go stab the queen in the face and then block, so I feel your pain... :)