Well, aren't you a killjoy? :)
If I am unable to run the game on 17th, I'll think about it then...

Confident I can play, just wondering about high.

i7 960 at 3.20 GHz
12 GB RAM
GTX 295

I know everyone is curious about their PC being able to run the game or not, but honestly, asking people how their respective machines will run in terms of high/low or fps is kinda pointless. There is absolutely nobody apart from the devs who can answer this. Why? because no one has played the game yet guys :)
I realise from the spec requirements you can get an idea but you never really can tell. For instance my PC didnt run Black Ops well. I am way past recommended settings but it just didn't run due to poor coding. I'm sure CD Projekt have done a great job but the only way to know other than spec requirements is to wait and see.

You can also use this.

http://www.systemrequirementslab.com/cyri/

Low to medium for me I think? Maybe high as XP requires less resources, but that may be pushing it. I should state that I need to run the game in a high resolution, due to my tele cutting off the left-hand side of the screen a bit if not set at the right resolution which is around 1824 X 1028 after adjustments have been made to the desktop.

Specs:

AMD Phenom 8450 Triple Core Processor

2.11ghz

3 GB RAM

Nvidia GeForce 9600 GT 512 MB RAM (I think this is actually 1.4 gig, according to system reqs lab? Never knew.)

WIndows XP

Same video card, Gil. It's not a bad one but it doesn't handle Dx11 Very High settings on Dragon Age 2 .. only High. (it's not possible to select Very high in game options)

I will only know what settings will I use when I install the game!

Quad 9550 @ 2.83GHz
8GB RAM DDR2
GeForce 9600 GT 512MB DDR3
1TB HD + 2TB HD
Win 7 Ultimate 64-bit
Reliably working for the past 2 years!

The developers have made it quite clear what the minimum system requirements are, and it does not take a lot of research to determine whether a GPU is below those minimum requirements.

Systems I have that just meet the minimum requirements can pull 10,000 to11,000 on the basic 3DMark06 benchmark.

That said, the minimum requirements are set very high, and it is a good guess that sub-minimum systems will still play the game at some level of competence. Thus the members who have some variation of the nVidia 9600 all have sub-minimum systems, but the 9600 is still a fairly strong GPU and ought to be able to play the game at some lower level of screen resolution and eye candy.

You guys think I'll able to max out the witcher 2?
spec:
i7 920 @ 2.7ghz
8GB Ram DDR3
Nvidia Geforce 460 GTX OC 1GB
Win7 64-bit

If not max at least a mix of max and high settings hopefully

Ei, how about mine?

AMD Athlon II X2 7750 2.71 GHZ
Palit GeForce 9800 GT 1024 MB Green Edition
3.5 GB RAM
Windows XP SP3

1152x864 screen resolution? I'm really afraid to go up beyond 1152, lol.

Battle stations reporting? So shall I.

Win7 64
Quad Core @ 3.2 Ghz
8GB DDR2
HD4870x2 2GB

Should be fine; lesser systems were seen to play the game on Ultra.
4:3 resolutions aren't supported, so you'll get letterboxed 1280x720 or something similar. You're above minimum, so you shouldn't have trouble with the game.
The initial posts from users who have Crossfire haven't been encouraging. But even without any gain from Crossfire (the 4870x2 is Crossfire on a single card), you're above "recommended" settings.

i have core 2duo e7500 2.93ghz , 9800gt , 4gb ram , windows xp sp3

will i run it properly ? plz reply soon ...

thank u wooglah .. i ran crysis 2 on extreme settings n got steady 30 fps ( i don mind 30 as its still smooth ) .. i hope ill b able to aleast put this on medium high

Well it's too early to tell if HIGH is the right word, but you will be able to run the game properly for sure. You will have to disable some effects and possibly use lower resolution if you decide to try high graphic settings.

I wonder how my rig will handle The Witcher 2. It runs Crysis 2 at a 40~50 FPS on high settings @ 1920X1080

Windows XP Pro SP2
AMD Athlon64 X2 6400+ Windsor Core
4GB PC6400 DDR800 w/ 4-4-4-12 timings
2 Geforce 9800GTX 512MB in SLI