I don't have any issues with these settings (attached).

I have the same problem. Crash in the police station. I have windows 10. (have tried many "things" ) It will not work!! Can someone help?

I also followed the suggestion of replacing 01.xarc with the file linked by a poster on the previous page and it worked perfectly. Win 10 x64.

To add my experience:

for me, the game was crashing on every video cutscene. NO GAME SETTING solved anything (tried all of them, as per countless advices on the forums).

I found two solutions that worked:

1. Running a program called CPU burn-in in the background. You do this so as to set it to run for several hours and you also set it to low priority in task manager, so that it doesn't actually compete with the game for CPU. The game will have priority.

2. Going to BIOS settings and setting the machine to only use 1 CPU core. Also, disable hyperthreading (if you have it). I also disabled Intel speedstep IIRC. In other words, disable all but one core and features that dynamically change CPU frequency.

I settled for the BIOS setting, so as to not waste electricity with CPU burn-in. Note, however, that entering the police station always crashed nevertheless. The police station required CPU burn-in to also run. Then it never crashed.

So, for a complete solution, I guess you would use both. To conserve electricity, only use CPU burn-in for entering the police station.

I tried another Browser it did not work, a friend of mine tried (with firefox) and it worked. Anyways I get the patch and The Longest Journey is working again. (after I limited the CPU)

For me the solution was really simple:

I started the game again, opened Task Manager, moved to the game's process (something obscure like game32.exe), set the process affinity to one CPU core only, then loaded the latest save game and the scene worked completely normally. No hassle with files or BIOS.

I suspect that this may not work for everyone though, but it's definetily the most simple thing to try first.
( I was running Win 7 at the time. Intel i7 2600k and Radeon 5870.)

None of these help me. It keeps crashing at the same point. Every. Single. Time. It's sad that such a cult classic never got the attention to get fixed. /disappointed

Ran into the same problem today. Replacing the Xarx-file worked. Like someone said downloading the file doesn't work with Firefox, I had to use Microsoft Edge.
I also made the changes in preferences.ini and ran in Windows 95 mode. Not sure if that was necessary though

This solved it for me too, without changing anything else.
However, the link works fine in Firefox, you just have to right-click and select "save link as".

can anyone re upload this file please?

Running on Win10 64-bit
I've tried EVERYTHING and nothing worked for me. The one thing that "fixed" it for me was enabling the time skip feature in the game settings. When I was on the screen with the crashed shuttle, I clicked on the stairs to get inside the police station and I just held down the ESC button. It skipped the faulty cutscene too quickly for it to crash the game. I saved after that and it was all good!

I am getting a message saying the file is not longer on the site for the Xarc file. I think it is plain old gone,nothing to do with which browser you are using. Any alterantive links?

I uploaded xarc file to google drive: 01.xarc