If you are running on Windows, my recommendation would be to right-click the SimCity 3000 Shortcut on your Desktop and open up the Properties. In the Shortcut tab, there is a line called "Target:". In the text next to it, add a space at the end of the text and type in "-intro:off" (Do not include the quotation (") marks when typing this in.)

It should now look like this:
https://www.gog.com/upload/forum/2017/02/96078aef4486b0f47f9f8de442af0082501f7c62.PNG

What this does is skip the video that plays when you start the game. For some reason the video that plays when you run SimCity 3000 has been known to crash the game on modern PCs. This parameter tells the game to skip it when you start the game from it's Desktop Shortcut.

If you are still encountering crashes, please provide more information on the crash. More specifically, When and Where it crashes, and How it crashes.