Eldgrim: Not sure GOG will fix it, i contacted the support, gave them a link to this forum thread and got a generic reply. I am annoyed,
I believe I found a fix, so I no longer have to run this in a virtual machine.
If you copy ddraw.dll and wined3d.dll from the WineD3D For Windows project (Google it) into your Alien Crossfire installation directory then it should work.
What this does is bypass Win11 implementation of DirectX, translating the API into OpenGL, which my GPU (and hopefully yours) supports.
Hopefully this will work for everyone. It would be nice if GOG and Steam could bundle this into the game files so this game remains accessible to others.
[EDIT] I thought this worked, but it just took more turns to crash. Thankfully my VM install is fine.