Vozisce: Hey, to anyone experiencing this problem in the future:
A couple of logo intro videos are shown and then the game stops responding.
A workaround is to install the game on the System Drive C:\
I have the game installed in C:\, but it stops responding after intro logos.
To be honest this was previously a D:\ drive, then I removed the C:\ drive and changed the D:\ drive to be C:\ drive. It shows as C:\, and Saints Row The Third Remastered works great from first open, Saints Row IV acts exactly like Gat out of Hell, expect that IV works if in Windows 95 compatibility mode (GOOH won't even open in W95 compatibility).
I'm on a MacBook Pro 16" with i7 9750H, 16 GB DDR4 2667 MHz, AMD Radeon Pro 5300M 4 GB GDDR6.
GOOH works from first open on an iMac 21,5" with i5 5575R, 8 GB LPDDR3 1867 MHz, and Intel Iris Pro 6100.
Both with Windows 10 Pro. I don't know what to do honestly, I would love to play it also on the MBP 16"...
EDIT: also problems with Saints Row 2, it hangs on Loading 5% on MBP 16" (it works on iMac) but eventually I had sort of "solved" it by porting it in macOS with Porting Kit.