MrElixer: You're better off playing it on easy first. RE is game about making decisions between save rooms and if you don't know what's coming you could screw yourself.
CDJ75: I haven't played this port yet but isn't the overall difficulty in the PC version based on the original japanese PS1 version's difficulty?
The japanese version is pretty easy as it is, even as Chris but especially Jill's campaign. Making her campaign even more easy by removing ink ribbons seems unnecessary.
I can confirm that the difficulty on this port from GOG is based on the japanese version from the consoles. Like every other PC port of this game, such as UK PowerVR.
The japanese version is easier than the western version. I might be wrong but I think the only differences are ink ribbon-less saves playing as Jill and the enemy hp overall, Yawn for instance (the big snake) it takes 4 acid rounds to kill on the japanese version and 5 acid rounds on the western version.
The difficulty label on character selection screen is just a label, nothing less, nothing more. Jill is meant to be easier just because she has more inventory space and ink ribbons aren't needed in order to save the game.
Jill has 8 inventory slots
Chris has 6
Jill has 96 HP give or take and Chris has 200 HP.
On the other hand, on western console versions of the game, the enemies have slightly more HP and both characters need ink ribbons to save. Characters HP and inventory space stay the same as the Japanese version.
It's always been like that ever since the original ps1 version.