According to this site: NOX PCGAMINGWIKI

You're supposed to be able to run widescreen and they have taken GOG as an example.

Is that it? Because whatever I do it doesn't work, I've tried different resolution 4:3 or 16:9, it won't change. Does anyone have an idea?

I'm the person who put that there, And it doesn't seem to be working now, Both custom resolutions and windowed worked when I tried a few weeks ago but now it doesn't, I've removed it, Sorry.

Does anybody else have anymore information for getting Widescreen to work? The folks over at WSGF were onto something, but only partial success.
http://www.wsgf.org/forums/viewtopic.php?f=64&t=17397

The PC Gaming Wiki fix worked fine for me. The resolution change doesn't show until you're out of the menu screens and into the game itself (after loading your save file). Also, if you go into the Options menu, it will reset your Nox.cfg file, so once you've edited Nox.cfg, do not go back into Options. Please let me know if this helps. -D

The most interesting resolutions to try and getting Nox to run for me isn't 1920x1080 or 1680x1050. The game crashes above 1024x768 I read, and people might think this is a failure. It isn't so, necessarily. I suggest looking at running NOX at either 840x525 (16:10) or 960x540 (16:9). If you don't know then these two resolutions is exactly half of the native resolutions at these aspects, which means non-blurry scaling, which is important for picture quality.

The advantages in short:

+non-blurry scaling + widescreen resolution
+more of a personal view then you'd get at e.g. 1080p (it's a preference in the end, of course)
+these resolutions isn't gameplay breaking. The game wasn't designed to have a viewing field over 1024x768 which might cause game-play related issues (undetermined)

I'm going to test this out myself later and report back, but I also read that it might not even work in multiplayer even if under 1024x768?, so that's a real bummer for me, if true.

Edit:

Check out the link below for how to run a few stable wide-screen resolutions (see the post my me on the linked page). Also, I've attached two pictures below of 640x480 as the baseline and one of 960x540, which is 16:9:

http://www.wsgf.org/forums/viewtopic.php?f=64&t=17397&p=155142#p155142

Credits: 'Saruman'

Use the link that Hippox99 provided and follow those instructions.

Some users might need to add a custom resolution to their graphic card settings through windows. On my laptop with Intel HD graphics I had to go into the graphic card resolution properties and add a custom resolution for 960x540. If you are using Intel HD the custom resolution that I added was 960x540 60hz 32bit color. Once I added this resolution, I edited the default.cfg and the nox.cfg to reflect the 960x540 settings and it worked.

Haven't played much but the resolution stuck (prior to that, it would just blink and go back to desktop).

Hope this helps.

Thanks, it seems to work alright.

None of these custom resolutions work under OS X. The menu loads, I try to load a game but the screen goes black then exits to desktop.

Hippox99, I tried doing exactly what you said to do in the linked post and added the custom resolution to my graphics cards settings as mjovanovic said to, but whenever I try to run the game at 960x540 it just immediately CTDs. Is there anything else that I need to do to make this work?

Bit of thread necromancy here.

Sadly, I couldn't get this solution to work for me. I'm using an Acer laptop with integrated graphics and the options you mentioned aren't present in the Intel HD Graphics software, so I wasn't able to modify them. From what I could gather, earlier iterations allowed you to change these options--but no longer. Is there a work around or am I just out of luck regarding widescreen play?

Editing my nox.cfg worked fine for me at native res, 1280*800

You saved my day.