If you haven't done so already install:
https://neverwintervault.org/project/nwn1/other/patch/169-critical-rebuild-english

Use WinXP SP3 compatibility mode

nwn.ini
[Alias]
;HD0=.\
;CD0=.\
;OVERRIDE=.\override
;TEMP=.\temp
;MODULES=.\modules
;LOGS=.\logs
;LOCALVAULT=.\localvault
;DMVAULT=.\dmvault
;SERVERVAULT=.\servervault
;TEMPCLIENT=.\tempclient
;SAVES=.\saves
;CURRENTGAME=.\currentgame
;HAK=.\hak
;PATCH=.\patch
;LNWMFiles=.\nwm
;AMBIENT=.\ambient
;MOVIES=.\movies
;MUSIC=.\music
[Display Options]
Width=1920
Height=1080
BitsPerPixels=32
RefreshRate=60
TexturePack=3
FullScreen=1
AllowWindowedMode=1
UseLargeFont=1
SafeMovie=1
Disable Movies=0
Disable Intro Movies=1
[Sound Options]
DisableSound=0
3D Provider=Miles Fast 2D Positional Audio
Environment Effects=0
Music Volume=0.50
Voice Volume=1.00
SoundFX Volume=1.00
Speaker Type=-1
2D3D Bias=1.00
Number 2D Voices=32
Number 3D Voices=32
[Config]
FirstRun=0
Connection=1
[Video Options]
VideoQualitySetting=3
Enable HardwareMouse=1
EnableEnvironmentShadows=1
CreatureShadowDetail=2
EnableGrass=1
EnableFastGrass=0
NumDynamicLights=8
NumShadowCastingLights=3
ShinyWater=0
CreatureWindSetting=2
EnableVisualEffectsHigh=1
EnableSkyboxes=2
AntiAliasing Mode=3
Enable VSync=1
Enable Truform=0
Enable AnisotropicFiltering=1
Grass Far Render Distance=900.0
Gamma=1.000000
Enable TextureAnimations=1
Enable CreatureEnvironmentMapping=1

nwnplayer.ini:
[Game Options]
Memory Level=100
Memory Access=2
CODEWORD=hacktastic
CODEWORD XP1=ffrodriguez
CODEWORD XP2=barkeater
TooltipDelay uSec=600000
Enable FloatyTextFeedback=1
Hide SecondStoryTiles=1
Single Player ItemLevelRestrictions=0
Single Player Enforce Legal Characters=0
Max Memory Usage=512
Client CPU Affinity=-2
ClientEntireChatWindowLogging=1
LogMyEmoteUsage=1
In-game Text Swear Filter=0
Visible Cloaks=1
Difficulty Level=3
Heartbeat Logging=1
Log Model Errors=0
Death Logging=1
MouseoverFeedback=1
TextBubbleMode=1
TargetingFeedbackMode=2

Edit:
Changed to Enable HardwareMouse=1 (needed 0 on linux)

Is this HD graphics you have on the laptop?

BTW, the problem is not unique onto HotU. It's just that the graphics demand get pushed farther with each expansion and further still with all the lastest community content, tilesets, animations, etc.

If it is crashing a lot, it is probably your computer that has a problem.

I have played HotU more than 6 times, it is very stable.

I run the game on a laptop with the same resolution and fairly garbage spec. On 2 year old drivers as AMD chucked this architecture under the bus. The first driver for it was the last on Win 10.

I also have Win 10 and I've had one crash across all the campaigns........in game. Can be a bit of trouble to get it started on occasion though. The other mods are running fine as well.

If you run an AMD/ATI card turn off shiny water, that and those cards don't get on. I do get a little lag here and there but it's playable.

You can also try setting your GFX card driver settings to every controlled by application. Older games don't like being overidden or even recognise some settings.

I don't know why, but now never crashed again.

It was crashing when ALT+Tabbing or 2/3 startups.. (so when I was launching it from Icon it succeded only 1/3 times, but then it continued without crashes).

Maybe now it stopped crashing because I rebooted the laptop? I've been alt-tabbing the Whole morning between NWN and NWN wiki without any more crashes :)