Works great @ my native 2560x1440 in Win10x64, version 1803, build 17128. The Scumm config auto-configures to my native screen res, but is also adjustable via the options panel (for instance, the VSR resolutions above my native 2560x1440--like 2880x1800 and up, will work fine, too.) RX-480 8GB, Adrenalins 18.3.3. No problems with Curse thus far.
The game will not allow running the game with aspect ratio turned off [switching it off just does nothing]--even though there is an option in the Scumm options panel for that (hit F5 in-game to bring up the full range of Scumm Options.) Despite resolution picked, Aspect ratio is always on, which means black borders on the sides for widescreen resolutions.
PS--when you go F5 for the menu, be sure and select "Return to Launcher" in order to get the entire host of SCUMM options. Adding FSAA improves the quality noticeably, especially at higher widescreen resolutions, imo, as does selecting 256-color display mode.
Post edited March 24, 2018 by waltc