I'm playing the game through Crossover for Mac, and it works fine. Occasionally, the game will crash, especially in the Goblin Warrens in Chapter 1. I do a Quick Save about every 2 minutes. Otherwise it runs fine except for the fact that the mouse will flicker.

If you're playing on a Mac, you'll need to play the game in Windowed Mode, not in Full Screen. Because the game was made for square monitors, and Macs are widescreen, the edges of the console will be cut off, meaning you can't get the screen to move. Also, the Gibberlings Widescreen Mod doesn't work on Macs, even through a cross-platform program.