DieRuhe: I'm going to re-install it and see what happens. If it's still messed up, I'll post a shot.
edit: when the game "runs", it does change my resolution automatically, but as you can see, the game window is way off to the right and too far down
Make sure that the game is not running and go to your IWD installation folder. Run the file 'config.exe'. Go to the 'Graphics' tab and check an appropriate resolution. Check your other preferences while you are there. If you still have problems, check the 'Windowed' box to get the game running in a window. While in-game go to Options > Graphics and check the 'Full Screen' checkbox. It should switch over to full screen, and hopefully be centered.