All great cRPG's have hard starts, like Gothic, Drakensang, Risen and Two Worlds. I is wise to do town quests and when travelling to stay on the road.
The very best mod for Oblivion, for example, as far as I am concerned, is Martigen's Monster Mod, as it does just that. It puts weaker creatures and Bandit's etc near towns and on roads, on the basis any dungeon near a town would get cleared out regularly by town guards. Also with patrols, bandits and creatures near the road would get thinned out too. As you went into the wilderness however, due to little human contact, creatures could breed longer, bandits could train longer, and therefore as you came across them, they would be much tougher. What MMM also did, which few other cRPG's do, is have factions, so that wolves would be more interested ion sheep than humans, unless they were starving, in which case they might even attack their own! By spawning different types of creatures in different ways, you would have packs of wolves of different sizes, some would have just fed, some would be starving, some would be large and brave and others small and cowardly. All this was random!
The Gothic series comes closest to this MMM mod, and has a "Radiant AI" system that knocks the pants off Oblivion's!