Porkdish: Titan Quest can be a fun game of balancing a spreadsheet in ancient rome.
adamzs: Not to nitpick or anything, but I think it's set in Ancient Greece. Granted, I've only played it for a couple of hours and that was years ago, so I might be wrong.
Greece, Egypt, Babylon, China, and Hades. Rome is the only main ancient empire that the game _doesn't_ touch. I'd also debate the "spreadsheet" part. I work with spreadsheets. I've played Titan Quest for a while. I don't see any similarities between the two. Every decent strategy game has more similarities to a spreadsheet than Titan Quest. Actually, I'd also debate the whole rest of the post, since only one or two skills per class do the thing that (according to the post) "a large number of them" do, but hey, everyone's entitled to his opinion. :)
Actually, I think, this thread has done a pretty good job in explaining the differences between the main games in the genre. While we certainly won't come to a consensus, I think this thread is pretty informative for those who consider buying one.