AndrewC: OK, I've only played for around 20 minutes and while it's enjoyable I find it to be under Diablo 3, especially because it's so hard to actually select an enemy to shoot at (playing a ranged class). This leads to either mis-clicking and moving instead of attacking or using the shift key to stay in place and not being in range.
Overall the style is nice and the game feels fun, but I'll wait for a sale first because Diablo 3 will keep me playing for a long time and second, because though fun, the little things (like the aformentioned shooting, or the highlight for objects with which you can interact with) managed to annoy me in the first 10 minutes of the game, which means that either I manage to get over them or play the game for a couple of hours and then stop
I've had trouble hitting the enemies as well at times. Also, one of the enemies pushed me through a wall.
But, this is still beta software, although I would hope that would have been fixed by now seeing as they're planning on releasing the game this summer.
In general it's a nice game, I can't wait to see how the singleplayer plays, those load screens are getting annoying.