Off the top of my head (may change in a few minutes):
1. Nox
2. American McGee's Alice
3. The Neverhood (I'm curious about it)
4. Ultima Underworld series
5. Advanced Dungeons & Dragons Masterpiece Collection (including Dark Sun: Shattered Lands, Dark Sun: Wake of the Ravager, Al-Qadim: The Genie's Curse, Menzoberranzan, Ravenloft: Stone Prophet, and Ravenloft: Strahd's Possession) :P
EDIT:
Drat! I totally forgot about Legacy of Kain: Blood Omen (the very first, rare isometric game in the series). Now that would be really awesome! Only, which game on the list would I replace with it...? Maybe Nox, as I already own it and could still play it on my Win98 computer (would love to be able to play it on Vista, too, though).
Post edited March 25, 2011 by Leroux