Tried Skyre once, might do again on my next playthrough - however, I actually intended to get my modding skills so far, that I can build my personal dreamhome first, so that may take a while. :)
Frostfall and Realistic needs.... don't know. Seems too much micro management for me.
Realistic Lightning Overhaul - tried it, loved and loathed it. As much as about any and all lights / weather mods, for all Bethesda games. I love what they achieve, but hate stumbling through the dark where I can barely see 5m/16ft, while blind falmers can shoot me across the screen....
Yes, the vanilla darkness isn't realistic, but I can't claim these mods are either. Don't know what it is, but they almost always seem to go with a darkness that's in a thick forest and from the technical view of a lens - ignoring that the human eye can and does adapt.
It's even worse for doing videos. I made a little series called
My Skyrim Khajiit and Argonian kids and I had a hard time with some shoots because of the lightning - and that in vanilla. I had to manually adjust the brightness level afterwards quite a bit and that really shows.
The only one I can recommend in the department is:
Climates Of Tamriel - Weather - Lighting - Audio What I use otherwise and might be interesting:
Better Dialogue Controls - never pick the wrong dialog line again.
Skyrim Project Optimization - as it says, improves the performance by expanding the occlusion culling technique already used in Skyrim.
Double Cursor Fix - prevents the Windows cursor appearing after alt+tabbing too often.
Acquisitive Soul Gems - fills souls only to corresponding soul gems. Never waste a grand soul gem again, because you accidentally stepped on a hare.
SkyTEST - Realistic Animals and Predators - animal behavior changes, like realistic foodchain / animals looking for water / animal cubs which follow their parents / last remaining wolf of a pack of 5 running away...
Interesting NPCs - simply the most impressive mod you can have for Skyrim. Adds 150 fully voiced NPCs, all with interesting backstories, some with quests / as followers....
Localized Thieves Guild Jobs - you can select in which city you want to take on a guild job.
Khajiit Speak - for Khajiit characters only. Changes your dialog to match the Khajiits as seen ingame. Khajiit can have that, yes?