Sachys: Actually, in the third he did all of his design work, went to see the preview and they had used none of it. It was one of the things that broke his love of his own work - along with that final debacle! (WHY SCOTT?! WHYyyyyYYYYYY!?).
When my net stops being crappy I'll try and find you the interview - quite an insight into how much he hated it all - and what could have been otherwise.
In fact, if i remember correctly, the film splice had something to do with what was supposed to appear in alien 3... but not sure if it was inspired by or directly based upon... must go check!
Edit: that said I still think the atmosphere, setting and some of the characters / scenes from 3 were brilliant!
Splice. Now that is a movie I need to see sometime! I remember seeing a preview for it.