I am running PG2 in Windows 7 Ultimate with 2 monitors. When I move the mouse to the right or side of the screen the screen doesn't scroll to the right and I've got to fiddle with trying to find a spot right on the edge just before I move to the second monitor.

Is there a way to run this title so that it isn't in windowed mode?

Your best bet would be to ask the question in the appropiate forum

http://www.gog.com/en/forum/panzer_general_series/#1321740003

I don't own the game, but the people over there do.

Thanks, didn't realize there was a forum for that game specifically. Sorry to have posted here.

Plugoff your second monitor? You don't need it for PG2.

As far as I recall, the reccomended way to do this in games that do not correctly capture the mouse (Damn you Half-Life) was with a program like Mouseclip which basically allows you to set a region of the screen where the mouse is allowed to move in. Not sure of how well this works, since I no longer have a second monitor to test it.