I can't work out the first or the seventh (and not sure the fourth, eighth or thirteenth are right either), but the other 21 are definitely correct.
EDIT: Unless there's a typing error in the fourth one ... in which case I've got it! But not the first one yet ...
The Horned Reaper (Dungeon Keeper)
Dr Fred Eddison (Maniac Mansion)
Manny Calavera (Grim Fandango)
A Bee (???)
Garrett (Thief)
Loom
Battle Isle (assumes a typing error in original post)
M. Bison & Co (Street Fighter)
Full Throttle
Guybrush Threepwood (Monkey Island)
The Nameless One (Planescape: Torment)
Discworld
Honda S (many racing games)
Vault Boy (Fallout)
Elvira: Mistress of Time (Elvira)
Legend of Kyrandia
Theme Park
Lula: The Sexy Empire
Syndicate
Jazz Jackrabbit
Outlaws
Crusader: No Remorse
The Neverhood
Bladerunner
Close Combat
Heart of Darkness