I also dislike if the game uses only auto saves in combination with longer save spans and increased occurrence of quick kills/instakills. I dislike even more is a cut scene without pause button support that are accessible only after long boss battle or long tedious activity.
toxicTom summed it up quite well.
toxicTom: ... I don't know how many times I died or otherwise messed up in a game because I got distracted by 12 kilos of 3-year-old jumping on me or hitting me with "a magic wand" or spilling her drink over me....
I don't live alone. Sometimes people simply come to my room and interrupt me. They ask me if I am free and even if they notice it is not the best time and back up, my attention is already lowered.
When I used to have on-call support, sometimes phone just started ringing and it wasn't an option to mute it or call back later when I am done.
The latest incident was The Lost Odyssey. It is inspired by Final Fantasy, save system included. I was killing my time waiting for a friend to pick me for weekend grill party. Of course, there was a part where you walked for long time without any save points in sight and in the end, just next to - for time being - unreachable save point, cut scene introducing time-demanding boss battle began.
Letting my friend waiting for me a hour isn't a valid choice in polite society, so I wasted half a hour of my time as a result.
Challenge isn't about grinding somewhat easy battles for 30 minutes and loosing a progress by crash, unexpected event or one wrong thumb move.
I would say having more play-style options works best. Does the person not be able to use manual auto saves? Sure, choose Ironman or something. Just like the last XCOM did that.