Or does the protagonist look a lot like Harrison Ford?

Yea I can see some resemblance.

Now that you mention it...yeah, he does!
I wonder if Harrison Ford gets a free copy for having a nearly digital replica of him in a game? ;)

If only he were voiced by Doug Lee...

At first I thought it was gonna be one of those deals like where Jean Reno sold his likeness to Capcom for Onimusha 3, and even provided his voice for his introductory scene (being a Jean Reno fan myself, I found it really weird to hear a stock VO actor's voice coming out of his likeness' mouth), but Capcom hasn't advertised any involvement with Ford. I mean, if you're gonna market a game, you may as well do it with star power.

It reminds me of Gorge Lucas's appearance in Perfect Dark. Good times...

Yeah, we tend to do that a bit.

Does he shoot first?

I can't beat ANY of the "psychos" in this game.

That seems to be a problem for a lot of people.
So far their suggestions have been to glitch them out, grind, or avoid if possible.

Ah, the dreaded psychos. On my current playthrough, I'm gunning for out and out level grinding simply ignoring the story completely. This puts you in a good position, defence wise, against the annoying buggers. Combo weapons also play a pivotal role in the battles since they have some of the highest damage per hit available. The nailbat is, imho, better then 70% of the other combos, both in speed and durability and maybe even damage dealt. Like tyler said, you have to grind them down.

This worked for me in three separate psycho battles, the first being the toilet one where I let him do the lunging attack, he misses and then I lay into him with the nailbat. After 1-2 hits, I get back, avoid his stab and let him jump into a cubicle again. It gets a little tedious, since you want to beat the hell out of him all in once, but if you hold that back, the bugger goes down eventually. With the crazed chef, I had 4 I.E.D's at my disposal which as soon as the battle started I quickly threw near where he regains health. This helped massively, since it's a one-two combo, explosion, then nails hitting him . With Slappy, I lured him to the ground floor and let him charge straight at me whilst I was near the water bar cave. He kept hitting the barrier, (since I climbed to higher ground right when he was near me) , resulting in him being dazed for a good while. You can either put a few shotgun shells in him, or like me, take a good chunk of health away with the nailbat.

Like I said though, I'm avoiding the story missions and just doing rescue missions, so I'm level 15/16 after 7 hours of playing it. By then you unlock better running speed, attack powers and more inventory slots. Each one helps with the boss/psycho battles.

Fire Axe + Sledgehammer = All Psychos worst nightmare.

The Psychos are manageable. You just need to bring painkiller drinks to psychofighst. Painkiller = beer + beer in mixer. Or some other drink that give a lot of health back.

And Katanas are pretty good at disposing Psychos. Actually Katana and Quick Step drink (beer + wine) is good combo.

I tend to die in the Psychos the first time I take the fight. Usually cause I'm expecting someone to take to safe house not a psycho. And usually I have couple of other people following me at the time. Luckily the time limits are very loose in DR2 so you can level up(rescue people) without rushing. Only things that are better to do right away are story mission.

Protagonist - Central character of a progressing story.

I think you mean 'main playable character'. Guybrush is a protagonist. Zombie Smasher Dude Pro Deluxe is not.

I don't actually see the resemblance. The nose is too big.