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http://www.youtube.com/watch?v=73b-JNV8nqs

This whole video is awesome. lol
Every cutscene from Giants: Citizen Kabuto is hilarious. Example: TIMMYYYYYY!!!!!
When I hear the words "humor" and "videogame" in the same sentence, Anachronox immediately comes to mind: https://www.youtube.com/watch?v=tSoko3qsJII.
I really didn't like the "JRPGish" gameplay, but every single situation in that game was so fun I could not stop playing until it was over!
Post edited January 11, 2014 by Enebias
When Indy puts an entire roasted boar into his leather jacket, most chuckle worthy.

And then he has the nerve to tell unsuspecting folks that he is selling those 'fine' leather jackets...
Monkey Island 1, you get thrown into sea with heavy weight (statue?) tied to your leg. Lots of sharp and edged objects around, but you just cant reach them... The solution to escape was pure brilliance.

If you dont happen to know this, just buy the damn game and see for youself ;)
Garrus: "When the Krogan names a Thresher Maw, you know we are in trouble."
Everything in Psychonauts
<- Look at my avatar :)
I still laugh so hard when Queen Deidranna slaps Elliot in Jagged Alliance 2 :D
Most dialogues in NOLF, especially the dialogue choices that you should NOT make if you want 100% completion (during briefings). Code phrases were good too.

Most Sam&Max (old and new), and for some reason the sitcom filming in particular.

and

Most Citizen Kabuto, as mentionned. In particular Borjoyzee scenes and, well, blindman's volcano.
Some of the dialog choices from Monkey Island 1 were just hysterical...

Me: I'm sorry. I didn't mean to call you cannonball-head.

Him: That's ok.

Me: I meant to call you chrome-dome!
Every bit of Conrad Verner dialog in Mass Effect 3
Broken sword 1
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Novotnus: <- Look at my avatar :)
Ha ha ha!

I don't get it.
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Wishbone: Every cutscene from Giants: Citizen Kabuto is hilarious. Example: TIMMYYYYYY!!!!!
Totally, one of the few games which actually made me laugh out loud frequently (whereas most "hilarious" games make me chuckle at best). And the Timmy! scene certainly gets the crown, I actually keep looking it up on YT from time to time.

Another game that made me laugh thousands of times was the "new" Bard's Tale (and that one along with Giants gets the crown for being the funniest game ever), sadly sharing the funniest moments would result in epic spoilers.
Post edited January 11, 2014 by F4LL0UT
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Novotnus: <- Look at my avatar :)
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F4LL0UT: Ha ha ha!

I don't get it.
http://youtu.be/2k_mpuPJQT4?t=8m32s
:)
Or, just watch from the beginning to get the story :) http://youtu.be/2k_mpuPJQT4