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Nope, but a victim of countless busted amiga and c64 joysticks in my youth though.
The only game to give my fingers and thumbs any sort of pain or discomfort whatsoever is:

Speedball 2

The Mega Drive version, Amiga version I could play all day - until I bust the joystick :D
Playing the MD game for about 2 hours straight always gave my left thumb some muscle strain and thats it. I don't even get sweaty hands while gaming :)
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dae6: Luckily, I stopped using this thing before any permanent damage was done.
What the fuck is that thing in the middle of the D-pad? I don't remember mine having one of them...

Actually, now I think about it, given that my hands have grown in the 15-20 years since I last used an SMS gamepad, I'm not sure I could actually hold one nowadays. They were very small things.
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Magnitus: Na, as a teen, I got myself one of those programmable controllers that saves and replicate an input sequence.

That took care of the fighting game which was the main source of sour thumbs.

Some people considered it cheating, but for me, crazy ass input combos wasn't so much an important part of the game as much as a strange Japanese fixation.
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hedwards: But, that is cheating. Otherwise they'd just use the Jaguar system with a million buttons and let you just type one key per combo.
It depends. I was cheating with regard to what the creators of the game wanted.

But for me, it was a stupid challenge that hurt my thumbs (that 180+ degree slide on the arrows was a real killer on the thumbs), so I improved the experience.
Post edited February 15, 2013 by Magnitus
I've gotten a few from yard work, but the closest I ever got with gaming was from the original Mario Party. Those "rotate the control stick" games were brutal.
I don't know about callouses but I do have nicotene stains on my fingers. I've got a silver spoon on a chain. I've got a grand piano to prop up my mortal remains.

Okay that was stupid. :P
DMC 3 did that to me on the ps2...heheh. It wasn't the special edition either.This was last year.
Not from gaming, but from our compulsory military service.
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hedwards: But, that is cheating. Otherwise they'd just use the Jaguar system with a million buttons and let you just type one key per combo.
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Magnitus: It depends. I was cheating with regard to what the creators of the game wanted.

But for me, it was a stupid challenge that hurt my thumbs (that 180+ degree slide on the arrows was a real killer on the thumbs), so I improved the experience.
No, it's cheating. It's not fundamentally any different than using cheat codes or a game genie, except that the people writing the game had no way of anticipating the cheating.
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Magnitus: It depends. I was cheating with regard to what the creators of the game wanted.

But for me, it was a stupid challenge that hurt my thumbs (that 180+ degree slide on the arrows was a real killer on the thumbs), so I improved the experience.
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hedwards: No, it's cheating. It's not fundamentally any different than using cheat codes or a game genie, except that the people writing the game had no way of anticipating the cheating.
So, whom exactly is he cheating, and what exactly is this person cheated of?
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hedwards: No, it's cheating. It's not fundamentally any different than using cheat codes or a game genie, except that the people writing the game had no way of anticipating the cheating.
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Psyringe: So, whom exactly is he cheating, and what exactly is this person cheated of?
What's that got to do with anything?

Cheating is cheating, I'm not aware of a different word in English for cheat codes in single player games. I don't really care one way or another, but all this rationalizing cheating tends to corrupt society before too long. It's one thing to decide that a game is too hard and to use a cheat code and another to delude yourself into thinking that you're not cheating.
Post edited February 15, 2013 by hedwards
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Psyringe: So, whom exactly is he cheating, and what exactly is this person cheated of?
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hedwards: What's that got to do with anything?
It's important to understand the context in which the alleged "cheating" has taken place. It's also important for the ethical evaluation of the act. So, I'm asking again: whom exactly is he cheating, and what exactly is this person cheated of? Try to answer the question instead of evading it. :)

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hedwards: Cheating is cheating, I'm not aware of a different word in English for cheat codes in single player games. I don't really care one way or another, but all this rationalizing cheating tends to corrupt society before too long.
Are you saying that a) cheating someone of his money by selling him a non-functional car, and b) using an aid to enhance one's enjoyment of a game, are the same thing? Or are you trying to construct a slippery slope in which one somehow leads to the other? I'm not sure I'm finding this line of thought entirely rational ...
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Psyringe: It's important to understand the context in which the alleged "cheating" has taken place.
No, it really isnt... he just stated that he used a trick outside the mechanics of the game to gain an advantage/more fun (usually known as "cheat")
It's just the common term used in the videogames context, and there is no need to have a "victim" of the cheat or to find any ethical evaluation (wth?) to label it that way...

Now, back to callouses.

From playing videogames, no, not reallly... but plenty from playing tennis.
However, back in the eighties, the whole Track&Field/Decathlon genre could be really punishing on your fingers, if you tried too hard!
Post edited February 15, 2013 by Antaniserse
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Psyringe: It's important to understand the context in which the alleged "cheating" has taken place.
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Antaniserse: No, it really isnt... he just stated that he used a trick outside the mechanics of the game to gain an advantage/more fun (usually known as "cheat")
there is no need to have a "victim" of the cheat or to find any ethical evaluation (wth?) to label it that way...
Ah, okay there is no victim. Good. So I suppose that nobody (because there was no victim) was not cheated of anything (because nobody could so far even _name_ what this nobody has been cheated of).

So, how do you label this action? And if you label it as "cheating", is it really the same as (say) cheating someone of his money by selling him a non-functional car? And do you really think that it will lead to a "corruption of society", as claimed in the mail that I responded to?
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hedwards: What's that got to do with anything?
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Psyringe: It's important to understand the context in which the alleged "cheating" has taken place. It's also important for the ethical evaluation of the act. So, I'm asking again: whom exactly is he cheating, and what exactly is this person cheated of? Try to answer the question instead of evading it. :)
I repeat, what on earth does that have to do with anything? English does not have a word for cheating in singleplayer and we don't have it because it's still cheating.

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hedwards: Cheating is cheating, I'm not aware of a different word in English for cheat codes in single player games. I don't really care one way or another, but all this rationalizing cheating tends to corrupt society before too long.
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Psyringe: Are you saying that a) cheating someone of his money by selling him a non-functional car, and b) using an aid to enhance one's enjoyment of a game, are the same thing? Or are you trying to construct a slippery slope in which one somehow leads to the other? I'm not sure I'm finding this line of thought entirely rational ...
No, I'm saying that the word is the same regardless of harm. Sort of like how we use the same word for homicide regardless of whether it's murder or manslaughter.

And it's not a slippery slope, I see this sort of rationalization all over the place rotting out society. And it's getting worse the more people that don't understand that they're making decisions of morality.
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Psyringe: Ah, okay there is no victim. Good. So I suppose that nobody (because there was no victim) was not cheated of anything (because nobody could so far even _name_ what this nobody has been cheated of).

So, how do you label this action? And if you label it as "cheating", is it really the same as (say) cheating someone of his money by selling him a non-functional car? And do you really think that it will lead to a "corruption of society", as claimed in the mail that I responded to?
Dude, what are you talking about?! it is just common videogames slang... you don't need to cheat anyone, you cheated the game

Infinite lives code? cheat
IDDQD? cheat
Macro to perform a combo with a single button? cheat

His 'corruption of society' was just an hyperbole to address the need to justify a "bad" (note the quotes?) action with some rationale