ShogunDarius: fair bit of negativity towards the software here, wasn't expecting that
Veneteaou: I didn't mean to come off sounding quite so negative. RPG Maker is a great program for people who don't want to code at all. Unfortunately, if a person doesn't want to code, then they choose to recycle old systems and mechanisms. In the case of RPG Maker, this means the game will be a top-down party-based RPG that will play like a watered-down Final Fantasy from the mid-90's.
So as I said, it's not worth the trouble unless you want a FF-clone.
This is not true at all.
RPG Maker is highly extensive if you know Ruby (which is coincidentally my language of choice today, as I'm a Rails developer) and you there are TONS of free available scripts made by the community to help other people - The Unify Community tutorials have nothing on the RPG Maker tutorials. Unity is a terrific engine to build pretty much anything, but in the specific case of 2D RPGs it certainly isn't the most suitable tool for the job because there's a clear superior contender on the market for that.
RPG Maker is great for those who don't know how to program but it's also a very nice tool for those who can program well, because it speeds the creation of the game by months or even years. If I decided to take the time to build an interface similar to that of RPG Maker I know it'd take a few years of my spare time, and I'd rather go to the important parts of developing games (story, game design, art) sooner rather than doing the low-level part all by myself when people have been there and done that very well before me.