rampancy: Everything seems to work as expected, including music, ambient sounds, and saving/loading games. The intro cutscenes also
do not play. Mods have not yet been tested.
igrok: I also tried it in Wine 1.8 and in Crossover (running patched 1.8.1), both with no overrides of any sort. It seems to work just fine. In Crossover there is flicker at the bottom of the screen when the intro cutscene is playing. In the stable version of Wine, there is no flicker, but I get a feeling it skips some frames.
That's interesting; in my experience, the cutscenes did play but all that I got was the audio with a dark screen. I should have been more specific earlier, and I've changed my post to reflect this.
rampancy: As per instructions on the AppDB and reddit, I also set offscreenrenderingmode=fbo, and UseGLSL=disable in winetricks.
shmerl: May be it's OS X specific issue, but on Linux you don't need that.
Thanks to you both for the extra pointers; I've amended my post with your information.