Here's my desktop.
The folders you see there, other than the GOG games folder, are works in progress (I'm a freelancer comic book letterer)... actually they're done, just waiting for the client to send updated scripts with corrections and additions (often he sends scripts with missing dialogue to save time and he fills the rest later). I'll make a backup when all that is done and then I'll delete them from the desktop.
As for the folder I've opened and the program I'm running right now is from a comic I lettered last year (did the second issue a couple of weeks ago), the client wanted to translate it to Spanish, so I'm currently working on that and hope to have it finished tomorrow.
The wallpaper fish is my logo. :)
tinyE: I got the folder idea from someone in here. It cleans up the desktop and is easier than going to the Start Menu to find the game.
I also use a folder to keep all my games in (even the ones that are not GOG games), I don't like having much stuff on my desktop and I like the circular GOG icons, so I keep them all in a folder instead of accessing through the Start menu. I customized my GOG folder to look like the website logo and I also customize several of the games icons, if I don't like the ones provided by GOG or if they don't work properly, sometimes they just don't scale right and look tiny.
EDIT: Oh, you can see I was listening to "I Started a Joke", lol, it's a cover I like from some youtubers.