dtgreene: I would argue that it is a failure on the part of the game designer, especially if the game doesn't alert you. Remember, even Wizardry 4 alerts you that you might get stuck after a certain point if you lack a certain item.
Sarisio: You didn't play Baldur's Gate I, did you?:) If you don't follow quests of your party members, and will go do some other stuff even for a bit, you will be out of time. There is no explicit timer either. Walkthrough is also needed because you want to get all your party members asap before they are level-scaled with DISASTROUS Max HP rolls and bad/missing proficiencies.
I played Baldur's Gate one without a walkthrough, and it's one of the few RPGs I finished. sure, I did some exploity stuff (like rerolling if my HP gain for a level was too low), and it's a game where you will totally abuse the save/reload function, but it can be done without any kind of guide. You will probably miss some stuff, and some things will be unoptimal (I had a "in party civil war" early in my game, with 2 of my characters trying to kill 2 others, and my main char looking powerless at the disaster. So a 40% no resurect casualty rate just before I hit a hard part of the early game), so it could drive off a completionnist/perfectionist or someone playing on harder difficulties, but it's far from unfeasible.