kusumahendra: Star Ocean 2, Beating final boss in 10 minutes, playing as Rena
That reminds me:
Star Ocean 2: Used Rena as my main, having her do some very nice damage with physical attacks. Alternatively, have her spam Star Flare, which casts quickly, targets all enemies, and interrupts the enemy's attack, so the enemies have trouble getting their attacks in. (Note that time stops during the spell animation, so it's effectively instant.) Meanwhile, I would use Opera or Noel for healing (because Rena is too busy doing other stuff).
I have read that, in Star Ocean 3, the game's main spellcaster (who, for whatever reason, doesn't join until late) can make an effective tank in the late game; you just need to set her up so that she has a lot of MP, keeps regenerating MP (MP regen is percentage based), and all damage she takes goes to her MP instead of her HP.