Yes! They already have it on cdp.pl DRM-free, so bring it on GOG, pretty please!
Already have Pursuit DVD but I'll gladly rebuy it here.

Here's a link. 44 hours to go and only halfway to their goal - looking grim.

Also, for those who still like their Cthulhu pen-n-papery, Chaosium is kickstarting the 7th Edition of the Call of Cthulhu tabletop RPG.

As a side note, I recently finished Darkness Within: In Pursuit of Loath Nolder, and I was really impressed. One of the best videogame takes on Lovecraft I've encountered, largely because it avoided the pitfalls that plague most games in the subgenre - it doesn't spam mythos monsters at you, it doesn't name-drop mythos tomes and deities like they were celebrities it met at a bar last night, it doesn't crowbar in an unnecessary apocalypse plot, and it avoids painting the walls in gore and actually gives you some oddly beautiful moments so the darker stuff has something to contrast with. Highly recommended for those who like their horror more atmospheric and less action-ey.

The Shalebridge Cradle level of Thief 3 has this sort of feel. Worth playing with the lights out and the volume cranked (or headphones). Good creepy atmosphere and awesome backstory that you discover as your progress through it. It also happens to be one of the longer levels in the game. Actually... It's probably the only level worth playing in that game.

(Warning : contains spoilers)
http://gillen.cream.org/thecradle.pdf

You can skip to it faster by using [url=http://www.fileplanet.com/169722/160000/fileinfo/Thief:-Deadly-Shadows---Savegames]these savegames[/url]. There's no level jump cheat code.

Here's a Let's Play of it. Watch to get a sense of it, but don't ruin it for yourself.

Penumbra have some elements too

Fall from Heaven 2, a dark fantasy-themed total conversion mod for Civ 4, is based partly on the Lovecraftian mythos and partly on the works of Poe, with some Celtic, Norse and Judeo-Christian mythology thrown in too. I've only just started to learn how to play it, however.

I was actually just looking at this game over the weekend. It looks like it might be more of a horror puzzle game like The 7the Guest or Dracula The Last Sanctuary. But there seems to be some sort of mechanic where you tell the game how to think of the answer instead of you thinking of it yourself. I'm still not sold on it though. Having an atmosperic horror title is fine by me, just as long as it doesn't go the Amnesia route and force phobias on you. I want to decide on my own what elements are scary, not have the game tell me "here is something that is supposed to scare you so we will disable all options except running away."

Shadow of the Comet is great, but was already mentioned, I recommend it to anyone.

I just finished playing Alan Wake (thanks to MoonGoddess!), and I don't think it has been mentioned but I had some strong Lovecraftian vibes from certain aspects of it. I don't want to say why because of spoilers etc. but it's worth a look if you haven't played it yet. I enjoyed it.

Edit: > One month later, I realize some atrocious spelling.

The "puzzles" are mostly inventory puzzles and tend to make sense in the context of the game, as opposed to the 7th Guest-style "Oh look, some careless person left a puzzle here, be a doll and solve it would you?"

The "thinking" mechanic is really just another form of inventory puzzle. As you read the numerous letters, journals, etc in the game, you can underline keywords which will then be added to your inventory as "clues". You can then combine clues the way you would combine items in other games in order to make deductions about the plot (e.g. so-and-so talked about gravedigging, town X has the nearest cemetery, I should go check out town X.)

I'll be honest, I was a little apprehensive about this mechanic, as it could easily have gone wrong - if the clues come too easily, you end up with the game telling you things instead of letting you figure them out. If they're too hard, you could end up in the position where you figured everything out long ago, but you have to wait for your impossibly slow-witted character to catch up to you. (Yeah I'm looking at you, Scratches.) However, for the most part I thought that this mechanic was actually very well-implemented and enjoyable. Clues mostly became available at exactly the time time that it occurred to me to look for them - for example, a character will mention something in a conversation that another character had referred to in a journal entry I read a while ago. At the time, that journal entry couldn't be underlined, because I had no reason to think it was significant. But now I think, "Hey, didn't so-and-so say something about that?" and when I go back, I find that now I can underline that clue and start combining it with other clues. I found that this actually made me feel like more of a detective, not less.

I'll just add to what Azilut is saying - there are quite a few optional tidbits, clues, leads, 'secret' locations etc. which (apart from affecting your "score" at the end, which is mostly just an indicator of how much of those You've missed) give additional background info, answers, tie up loose end etc. So there's additional "aha" moments throughout the game, and it adds a bit of replayability as well.

Personally I can't recommend In Pursuit of Loath Nolder enough, it's a shame it went so under the radar. I enjoyed the second one as well (more memorable 'secrets' to be uncovered and the atmosphere is still stellar), it's fully 3D instead of node-based this time, but it gets less subtle with the Mythos references (nothing crazy though, at least not until the end) and it feels a bit unfinished really, leaves some unanswered questions. Still, I really enjoyed it as a follow up.

Just found another game, I think not mentioned before:
Oz Orwell and the Crawling Chaos by Midian, oldschool adventure.
€3+VAT
Here is a review of it on AdventureGames.

I think we can add Magrunner: Dark Pulse to the suggestions in this thread now. I noticed it wasn't mentioned yet.

Here's another one - Cryptic Comet's new game, The Occult Chronicles, is now available for Buy-In Beta for $14.99. Supposedly the game is now content complete, and is in the late stages of bug testing and balancing.

This is the same guy who did Armageddon Empires and Solium Infernum, so I have high hopes for this one. It looks to be a horror roguelike loosely inspired by the board game "Betrayal at House on the HIll", with Cthulhu elements mixed in for good measure. Hopefully I'll get a chance to take it for a spin tomorrow - I'll report back if I do.

I've played it - personally, I like it a lot. Unfortunately, it didn't sell very well. I think most people tried to play it as a combat game like Magic: The Gathering, and yeah, if you approach it like that then it isn't going to compare very well. But that's because it's really more of a storytelling game like Once Upon a Time, with a bit of combat thrown in to spice things up. If you approach it with that in mind, it actually shines as a very thematic experience.

I remember friends at Uni having decks about 15 ears ago, it seemed pretty interesting and cool