Thank you guys for the tips on tweaking Batman: Arkham Asylum, they made me believe playing Arkham City is still a possibility ;) I considered this possibility before, but my pride won't let me give up on the game for that, lol. I've played quite a few games that had their share of hard puzzles (Magrunner, Spacechem and Braid come to mind), but none of them gave me such headaches (literally).

Nope. Having to do such a thing every time before playing a specific game doesn't sound that exciting...

Plus can you imagine having to explain to your friends why you keep a box of Dramamine next to your computer? :P

It's not to get you high or anything, It's to take away the motion sickness. I'm sure the game should be exciting enough as it is. :)

It was just a suggestion! Every experiment needs someone to test out the theory. Fortunately, I don't suffer from motion sickness (in fact I love Roller Coasters, which is why I own No Limits).

However, one of my children used to get sick in the car on long trips and the Dramamine helped. I wouldn't mind explaining to a friend that one might get motion sick... you never know if they would ever invite you to go on an airplane ride or boat trip. :)

I usually don't have that a lot, but I experienced this a bit when trying out Dark Forces 2, and in that case I noticed it was because the camera movement was not quite fluent on my setup, but visibly gradual. It was always lagging just a tiny bit behind, when I looked around with the mouse. Maybe that could in part be a cause for the dizziness, that you think you're in control but the camera doesn't obey your mouse movements 100%, so that when the eyes expect to be somewhere else already, the visual display is lagging just a tiny fraction of a second behind.

I would still be curious to see if it has any effect on those who get motion sick from playing the types of games which have many degrees of freedom and motion.

I wouldn't think so honestly because whenever I needed Dramamine it was my whole environment that caused the problems. Like if you are on a boat and get sick it's not just what you are seeing that's doing it, it's also the rocking, the creaking, the smell; a million things you don't get when you ate sitting at a computer, which I might add, you can always just turn off; not an option on a boat or a roller coaster.

Isn't the old sailor's trick to look at a fixed point? I'm lucky in that I never became seasick. And whatever you do, DON'T look out a porthole!

THAT NEVER WORKS!!!!!

I was on a boat before and believe it or not, the rocking actually was soothing, best night 's sleep I ever had. On roller-coasters, I love to look around and view the gestalt as it gets higher and higher, and even watch as it loops. There's just something really cool about it; but I see a lot of people close their eyes.
You want to look at a "fixed point" when you're navigating, not when you're feeling sea-sick. The fixed point allows you to move forward without going in circles (which I suppose could make people sea-sick).

Hydrophobia: Prophecy ended up giving me a headache and made me feel a bit sick at times. Not sure if it was the depth of field or the fact that nearly everything in the game is grey with only rare bits of color, plus the water sloshing everywhere. Or maybe it was because it was a bad game and my brain was telling me to quit playing it.

Apart from Beathazard already mentioned, I would say GTA Online when you do an off-road bike race and the dumb host locks the view of players to FPS, it feels like being on a boat caught in a storm X100 :(

Resident Evil: Revelations, The FOV didn't even bother me aside from being annoying. It was the insane amount of motion blur that did me in. Once an option was patched in to disable it I could finally play.
Didn't fix the mouse movement though. :P
A bit of everything? :P

Daggerfall does this, which is a shame because the Class/Spell/Item Makers are fun to play with, even though they're not exactly balanced.

All grey? There were plenty of neon lights if I recall. Wasn't a groundbreaking game by any stretch of the imagination, but I kinda felt it did a lot better job of making you feel in danger of the structure collapsing and you drowning than Bioshock did after the initial five minutes.

Regarding the getting queasy with games like Descent, Pulse Shift and a bunch of other games where you need to navigate but aren't walking. I'm guessing the human mind tends to build a mental map of the area to navigate. When you twist around and can't quite tell what is down anymore your brain struggles to navigate which could result in a headache. I'm guessing it's something that could be trained though.

Descent like games are a bit too monotone in walls that you can't easily tell which way is "down" and where your mental map is. Pulse Shift, Tri and a couple of other games have you walking on the "floor", but what is floor can change and thus if you're looking for an exit or a path, suddenly having a wall be a floor and thus not an obstacle could throw your mental map off balance to a point you get seasick.

Also, honorable mention for me to Dead Space 1 on the PC. It was giving me a headache right until I turned off VSync. The VSync tried to smooth your mouseinput which actually just resulted in lag, so a swift movement of the mouse would have the camera swiveling for longer than the mouse movement, but not as fast.