OneFiercePuppy: I would never argue that Divine Favor isn't powerful (it's crazy) but I would say it's not necessary. You can get by without it, but you can't get by without high skills. If you're willing to drop STR & END to 4 though, you *can* get both if you take Gifted, and still have the points free to make a godmode plasma rifle sniper.
It may depend on the playing style (and that I was playing the modded version), but at the end of the game I don't recall thinking "damn I wish I could have bumped that and that skill even further", but I did feel I would have wanted to pick a few more useful perks for my characters before the last mission.
I recall with my builds I was able to get high enough skills for all the relevant skills for all my team members, even though I had a max number of team mates (which meant I'd get less skill points per team member). E.g. the important shooting skills (small guns and energy weapons) were at about 160% or so. It became harder and harder to push them further anyway, as the game heavily penalized you if you pushed your skills well beyond 100%, like taking 2-3 skill points for advancing the skill by 1%.
I guess I also specialized somewhat, so I didn't try to make all my team members jack of all trades. I tried to make them all pretty good sharpshooters so that they could cause damage from long distances accurately, but on top of that one or two concentrated on heavy weapons as their secondary weapons while the rest concentrated on energy weapons, only one of them was a good medic IIRC, only one of them needed to have good skills for computers etc. Specializing also saved skill points.
That is not to say I didn't try to get INT high as well, and I also think I might have picked a perk to get more skill points for some of my team members as well (since I could get perks more often, after all).
Anyway, your mileage may certainly vary, these were just what I found out playing the modded version, and restarting it from the scratch when I was already quite far in the game (because I just couldn't get over of having made some poor character decisions earlier in the game).