sreiches: As the title says, any time I try to launch a game that uses a DosBOX shell, whether downloaded and installed by way of the Galaxy client or directly from the GOG website, DosBOX launches and then locks up.

Games I've had this issue with so far:
Syndicate Plus
Realms of Chaos
Shattered Steel

I also had a DirectDraw3D related crash in XIII, but GOG support for that one has been wonky for a while.

And, perhaps unrelated, Nox makes it through the initial videos and then I just get a flickering image of the logo.

I've never had problems like these with GOG releases in the past.

justanoldgamer: Syndicate Plus is supported in Windows 10, I only checked that one but I suppose the other DOSBOX dependent games are also supported.

As WVPR says, check the dosbox version. I would add to check if you have the latest GOG version of the game, I think Galaxy is suppose to take care of that (I don't use it) but it does not hurt to check. I know you said you also downloaded them directly but you don't say when. (I hope I do not sound rude but 3 decades of professional and amateur tech support thought me to not assume anything)

The latest official release of DOSBOX what 0.74 in 2010, I think it was in the Vista era. GOG says the game is supported on Windows 10 which I assume means they tested it. If you have the latest GOG version and it works on their Windows 10 machine then the likely culprit is your computer (including stuff like video card/chip, sound card/chip, and drivers) and the software it runs in the background like but not limited to anti-malware (anti-virus, firewall etc...)

By saying it is your computer's fault I am not saying it is your fault or that GOG is not responsible, I'm just saying that computers are amazingly complex beasts and I spend my days amazed that they work at all. For example, there is a game, I forget which one right now, who won't run with the driver of my logitech mouse active, I have to use window's generic mouse driver for the game to run.

Not running Windows 10 I can't really help you but providing all information you can think about your machine might help someone who can.

So, what is the brand name if any, memory amount and speed, cpu type and speed, memory type and speed, video card model (or integrated video model), same thing for soundcard, mouse. I've never seen a monitor causing a program to cause the type of issues you're having but throw in its model just in case. Antivirus, firewall, programs that you're always running in the background like a music player or a scheduler reminding you to eat and sleep, anything but the computer's color and your favorite beverage while gaming (do share if it's a good beer).

If you do not know some of that information or how to get it, that's ok, if it is important I'm sure someone will help you figure it out.

This post written under the influence of the following beer:

sreiches: As the title says, any time I try to launch a game that uses a DosBOX shell, whether downloaded and installed by way of the Galaxy client or directly from the GOG website, DosBOX launches and then locks up.

Games I've had this issue with so far:
Syndicate Plus
Realms of Chaos
Shattered Steel

I also had a DirectDraw3D related crash in XIII, but GOG support for that one has been wonky for a while.

And, perhaps unrelated, Nox makes it through the initial videos and then I just get a flickering image of the logo.

I've never had problems like these with GOG releases in the past.

fortune_p_dawg: i was having a very similar problem last night. do you have an xbox one controller plugged into your computer? it was completely hitching dosbox up for me.

sreiches: Oh, I do! I'll try unplugging it.

EDIT: Yep. DosBOX is no longer crashing.