I'm on Debian 64 bit and have Dosbox installed, with the terminal It keeps saying I have no permission even though I did chmod 777 and +x. I can launch the config file but not the game, it opens and then it simply crash. Quite a bit disappointed it should be removed from the store at this state.

DId a quick video, hopefully it helps. https://www.youtube.com/watch?v=oR07c65Ls90&feature=youtu.be

EDIT: I was able to play while using Lutris and then launch it with Dosbox.

Running 64 bit, I will check how to do a system report. I know being root is dangerous but I thought it was okay to run something like a game, won't do it again. Thank you I will give a try and see if it works, if it doesn't I will send you a report.

I just picked this game up. It's not working for me either.

This is what I am getting when running it from terminal

Running Eradicator
Starting Eradicator
DOSBox version 0.74
Copyright 2002-2010 DOSBox Team, published under GNU GPL.
---
CONFIG:Loading primary settings from config file dosbox_eradicator.conf
CONFIG:Loading additional settings from config file dosbox_eradicator_launch_linux.conf
Memory sizes above 31 MB are NOT recommended.
Stick with the default values unless you are absolutely certain.
MIXER:Got different values from SDL: freq 44100, blocksize 512
ALSA:Can't subscribe to MIDI port (65:0) nor (17:0)
MIDI:Opened device:none
One joystick reported, initializing with 4axis
Using joystick Logitech Gamepad F310 with 6 axes, 11 buttons and 1 hat(s)
DOSBox switched to max cycles, because of the setting: cycles=auto. If the game runs too fast try a fixed cycles amount in DOSBox's options.
./launch_eradicator_game.sh: line 20: 30333 Segmentation fault "${CURRENT_DIR}/dosbox" "-conf" "dosbox_eradicator.conf" "-conf" "dosbox_eradicator_launch_linux.conf" "-noconsole" "$*"

For Ubuntu 18.04 x86_64
It works if you
sudo apt-get install build-essential
sudo apt-get install gcc-multilib g++-multilib
sudo apt-get install dosbox:i386
sudo apt-get install lib32z1-dev

Then download libpng-1.2.10 source code
Compile it with
export CC="gcc -m32"
export CXX="g++ -m32"
./configure --prefix=/usr --libdir=/usr/lib32
make
sudo make install

In the Eradicator directory edit start.sh
Change the three occurrences of x86_64 (after uname -i) to x86 or anything but x86_64

Change in game/x32/dosbox_linux and
chmod -R u+x *

Then go back to the Eradicator directory

Then excute start.sh and it should work.
./start.sh

For Debian x86_64
The first thing to do is as root
dpkg --add-architecture i386
apt-get update
Then the Ubuntu x86_64 instructions should work