VanishedOne: I had trouble clicking on objects because the screen shake would move them around under my mouse pointer. If I misclicked, my characters might treat it as an instruction to walk into danger.
Hickory: I have similar trouble with character animations during battle. How many times have I targeted an enemy and fired, only to have their animation move (effectively negating the target) right at the crucial moment. It's infuriating when it costs vital action points, all because target toon is doing some over-exaggerated boredom/stance-shifting dance. Such animations should be disabled during battle, considering there is a penalty to-hit anyway.
I had this one last night, against the lighthouse boss (yes, I'm playing really slowly! ha!). The odd thing is that many times I have to double-click to get one of my characters to move but this time she (my archer, no less) just zipped right on over next to the boss as I clicked for her to shoot him and he happened to go into his jump / dance-around animation at the same moment.
After that, I did try targeting via the strip of combatants across the top of the screen but it was really hit-or-miss (no pun intended) whether or not I could target someone this way. I'll have to play around with it a bit to see if I was messing up somehow.
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I would also welcome a pause feature, as it can be difficult to prepare for a battle as the clock is ticking on your enchantments, AoE spells, etc., especially trying to juggle these efforts for four characters.