galneon: You don't take your RSI seriously as your priority is playing and whining about video games, so I didn't take it seriously either. You said we only need the four face buttons and two shoulder buttons for D1 on PC (which could not be less true). That happens to match the layout of the SNES gamepad. I put the image out there of someone playing Diablo on an SNES gamepad to demonstrate the absurdity of your wishes and of your indignation that they were not fulfilled.
MikeydscEradicus: Look, obviously you have no clue about RSI and causes, effects. I advise you to be quiet on matters you have no knowledge as you are making yourself look like a fool. Get educated then come back and we can talk.
The PC mouse causes effects such as dorsiflexion - I will give you minute to go look it up.
Controllers are more naturally fitted to sooth this but what do you know anyways.
I have my answer that it does not come configured with a controller.
I dealt with RSI as a teenager. At early signs and warning from my doctor, I reined in vices, like excessive gaming, and today my wrists are fine. I'm sorry if you've let it go beyond the point where you can deal with it through nonsurgical means. If it's so bad, I'm not sure why you're wasting your time and comfort typing here.
I don't know what kind of mice you're holding from what perverse angles, but I hold my mice and trackball with a neutral wrist, in neither palmarflexion nor dorsiflexion. The trackball facilitates this automatically, while mice require a wrist-rest, an ergonomic standard since the '90s (which you apparently did not use :(). While my gamepad posture is more dynamic, I often hold them with one or both wrists in dorsiflexion. Considering I'm trained in anatomy and kinesiology, I can actually understand the Wikipedia description you read and, most likely, misinterpreted. Love that I'm being implored to educate myself by the guy who started a thread based on the false premise of Diablo being "originally controller-based," though. You're trying too hard here, and too little in real life. Get off the PC.