Blarg: Interestingly, I can get even sicker when not paying close attention to the game. If I look at t.v. for a while as a descent demo is playing in the background, I will get nauseous VERY fast. Turning head on immediately soothes my stomach. Paying very close fixated attention to the screen and my feeling of what is top and bottom seems to work wonders to keep me oriented, thus not triggering my inner ear that weird stuff is going on, thus not making me sick nearly as quickly or as badly.
There's actually a good reason why only seeing the edge of the screen is worse.
One of the reasons for getting motion sick while playing games is because objects at the edge of the screen warp and change shape as they move across the screen. A sphere at the edge of the screen will be more of an oval shape, will squash into a circle as it moves towards the centre of the screen, then stretch back out into an oval as it approaches the edge again. It's a result of projecting 3D objects onto a flat surface. It makes your brain think you've eaten the wrong kind of mushroom (solid objects should not behave that way!), thus your body tries to flush your digestive tract as quickly as possible...
For a real puketastic time, try playing as the alien in Alien vs. Predator. The extra-wide FOV makes this distortion even more pronounced.