I just bought One Unit Whole Blood, and for the most part it seems to run alright. When I am in a room with glass, water, a mirror, close to a tree or other sprites, however, the game slows down significantly. I realize that Dosbox is an emulator which is demanding on the system, but I have heard of people who can run Blood on Dosbox on 1280x1024. I am only running on 800x600, if I go up to a resolution as high as 1280x1024 the frames per second are very low. Here are my system specs:

Intel Core 2 Quad 3.00 GHz
Radeon HD 4870 1GB (Catalyst 10.7)
6 GB DDR3 RAM
Windows 7 Professional 64-bit

Does the game behave this way for most people or is there something about my machine that would be causing a problem? Thanks for any replies.

That's normal when you use dosbox. Also FYI: Blood originally has never been meant to be played in resolution higher than 800x600.

Plays perfectly fine on my machine, with no slow-downs:

XP x64
Core 2 Duo 3.33ghz
GTX280
4gb memory

Maybe an ATI driver issue?
Try going back a LONG way to old old drivers and see if it works better.

My machine is not nearly as powerful and it runs Blood just fine inside DOSBox. Try different graphics settings maybe?

shouldn't influence much. The dynamic core generates machine code itself and doesn't depend on the cpu dosbox is compiled with/for.

Yeah, I figured, but with the hardware specs listed, that's the only thing I could think that might be a factor. Unless of course Vdaxzter let some one hose his box with spyware and what not.

I'm running on an older Core 2 and I get a consistent 35-50FPS running at 800x600.

The latest version of DOSBox offers better performance with Blood than the version the game comes packed with. You may get better performance if you update it. I know I did.

You might want to try putting the cycles on max and core on dynamic in DOSBox settings or DOSBox.conf. You can, in addition, also try a different output renderer, such as OpenGL, OpenGLNB, or ddraw. For me OpenGLNB seems to be the fasted. I don't own the GOG Blood version, but Blood uses more memory then what is default in DOSBox, so you can also increase the memory in DOSBox to the max: 63. Also DOSBox 0.74 has a (huge) speed improvement compared to older versions so trying that also might not be such a bad idea.