I've been using Vista since last December, and I haven't had much issues with it so far.
The only problem I really have is that it's putting my files all over the place, and I like to micromanage where I put things on my hard drive. Vista kind of seems to take that freedom away.
Other than that, after finishing my tweaking. I haven't seen a single BSOD nor had much issues with Vista as a whole. The only problem it might have is that it's a resource hog, and you need beyond decent hardware to run it. Which I admit is a fault if you're looking at an OS.
I'm quite pleased that Microsoft is still trying to maintain backward compatibility in some ways. For the abandonware scene, as well as the folks who like their old good games it might make things a little easier to run them ol' programs. ^.^
If I were you Andy, I'd wait on purchasing Vista a little longer though. Microsoft has
supposedly a deal in the works going that folks who buy Vista in July and later can upgrade to windows 7 for free! Check the source of that kind of deal in link below:
http://www.techarp.com/showarticle.aspx?artno=609&pgno=0 General consensus seems to be that any Vista license bought from 1st of July 2009 and onward is viable for a free upgrade to 7. So perhaps patience is a virtue in this? ;-)
Edit: MS hasn't confirmed nor denied this, changed my post a bit to make that more clear.